A NEW METHOD FOR THE PRODUCTION OF LARGE SPHERICAL MONOSIZED POLYMER PARTICLES FOR BIOMEDICAL AND CHROMATOGRAPHIC APPLICATIONS

被引：7

作者：

COLVIN, M ^{[1
]}

CHUNG, SK ^{[1
]}

HYSON, MT ^{[1
]}

CHANG, M ^{[1
]}

RHIM, WK ^{[1
]}

机构：

[1] CALTECH,JET PROP LAB,PASADENA,CA 91109

来源：

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 1990年 / 28卷 / 08期

关键词：

D O I：

10.1002/pola.1990.080280806

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Monosized droplets of 2‐hydroxyethyl methacrylate (HEMA) and glycerol monomethacrylate (GMA) were made by passing the monomers under pressure through a nozzle coupled to an energized piezoelectric crystal. The droplets were allowed to fall into liquid nitrogen where they vitrified. The radiation post‐polymerization of the monomer spheres was investigated. Uniform monosized poly‐HEMA particles in the 100–300 μm diameter range were prepared with a coefficient of variation of 1.57% for particles of 155 μm in diameter. Monosized poly‐GMA was also prepared. The post‐polymerization conversion of pre‐irradiated GMA vitrified monomer droplets as a function of thawing rate and radiation dosage was investigated. Copyright © 1990 John Wiley & Sons, Inc.

引用

页码：2085 / 2095

页数：11

共 11 条

[1]

ALFREY T, 1954, J OPT SOC AM, V44, P603

[2] STUDY OF POST-RADIATION POLYMERIZATION OF 2-HYDROXYETHYL METHACRYLATE GAMMA-IRRADIATED IN CRYSTALLINE AND VITREOUS STATES [J].