NEW DOLABELLANE DERIVATIVES FROM THE BROWN ALGA DICTYOTA-PARDALIS

被引:17
作者
WRIGHT, AD [1 ]
KONIG, GM [1 ]
STICHER, O [1 ]
LUBINI, P [1 ]
HOFMANN, P [1 ]
DOBLER, M [1 ]
机构
[1] SWISS FED INST TECHNOL,DEPT ORGAN CHEM,CH-8092 ZURICH,SWITZERLAND
关键词
D O I
10.1002/hlca.19910740822
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Reinvestigation of the brown alga Dictyota pardalis f. pseudohamata CRIBB led to the crystallization of 1 and to the isolation of the two new dolabellane derivatives 2 and 3. X-Ray analysis of 1 and 2, together with detailed 1D-and 2D-NMR studies on 2 and 3, allowed their structures to be elucidated as (1R*,3S*,7S*,11R*,4Z)-dolabella-4,8(17),12(18)-triene-3,7-diol (1), (1R*,3S*,4S*,7S*,8S*,11R*,14R*,12E)-3,4:7,8-diepoxydolabell?? -12-ene-14, 18-diol (2), and (1R*,3S*,4S*,7S*,8S*,11S*,14R*)-3,4:7,8-diepoxy-1,4,8,12,?? 12-pentamethylbicyclo[9.3.0]tetradecan-14-ol (3).
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页码:1801 / 1807
页数:7
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