DETECTION OF EPSTEIN-BARR-VIRUS DNA IN A JAPANESE CASE OF LYMPHOEPITHELIOMA-LIKE THYMIC CARCINOMA

被引：23

作者：

MATSUNO, Y ^{[1
]}

MUKAI, K ^{[1
]}

UHARA, H ^{[1
]}

AKAO, I ^{[1
]}

FURUYA, S ^{[1
]}

SATO, Y ^{[1
]}

HIROHASHI, S ^{[1
]}

SHIMOSATO, Y ^{[1
]}

机构：

[1] NATL CANC CTR,DIV CLIN LAB,TOKYO 104,JAPAN

来源：

JAPANESE JOURNAL OF CANCER RESEARCH | 1992年 / 83卷 / 02期

关键词：

EPSTEIN-BARR VIRUS; THYMUS; LYMPHOEPITHELIOMA; POLYMERASE CHAIN REACTION; VIRAL ONCOGENESIS;

D O I：

10.1111/j.1349-7006.1992.tb00075.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Epstein-Barr virus DNA was detected in a case of lymphoepithelioma-like thymic carcinoma. A homogeneous terminal structure of the viral DNA was demonstrated in this case, indicating the presence of the viral genome in clonally expanded tumor cells. Since all of 26 other thymic epithelial tumors (eight non-invasive, 13 invasive thymomas and four non-lymphoepithelioma-like thymic carcinomas) in Japanese were negative by polymerase chain reaction, it is suggested that lymphoepithelioma-like thymic carcinoma may represent a unique pathological entity distinct from Epstein-Barr virus-negative thymic epithelial tumors, which are in the majority in Japan.

引用

页码：127 / 130

页数：4

共 15 条

[1] LYMPHOEPITHELIOMA-LIKE CARCINOMA OF THE LUNG [J].