DOSAGE COMPENSATION OF THE DROSOPHILA-PSEUDOOBSCURA HSP82 GENE AND THE DROSOPHILA-MELANOGASTER ADH GENE AT ECTOPIC SITES IN DROSOPHILA-MELANOGASTER

被引：20

作者：

SASS, H ^{[1
]}

MESELSON, M ^{[1
]}

机构：

[1] HARVARD UNIV,DEPT BIOCHEM & MOLEC BIOL,CAMBRIDGE,MA 02138

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1991年 / 88卷 / 15期

关键词：

GENE CONTROL; POSITION EFFECT; P-ELEMENT TRANSFORMATION; RNA PROBE PROTECTION;

D O I：

10.1073/pnas.88.15.6795

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Measurements were made of the amounts of larval RNA transcribed from the autosomal Adh gene of Drosophila melanogaster and the X chromosomal Hsp82 gene of Drosophila pseudoobscura carried on the same P-element transposon inserted at various sites in the D. melanogaster genome. Both genes were fully compensated at sites in euchromatic regions of the X chromosome but neither was compensated at a site in the centric beta-heterochromatin of the X chromosome. No compensation of the D. pseudoobscura Hsp82 gene was found at any of 10 autosomal insertion sites tested. The compensation behavior of the transposed genes was, therefore, not determined by closely linked sequences but instead was determined in each case by their new chromosomal environment.

引用

页码：6795 / 6799

页数：5

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