CHEMOPREVENTION

被引：94

作者：

GREENWALD, P

KELLOFF, G

BURCHWHITMAN, C

KRAMER, BS

机构：

[1] Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, Maryland

[2] Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, Maryland

[3] Division of Cancer Prevention and Control, National Cancer Institute, Bethesda, Maryland

[4] Associate in the Division of Cancer Prevention and, Control of the National Cancer Institute in Bethesda, Maryland

来源：

CA-A CANCER JOURNAL FOR CLINICIANS | 1995年 / 45卷 / 01期

关键词：

D O I：

10.3322/canjclin.45.1.31

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chemoprevention has been shown to be an extremely promising approach to the prevention of invasive cancer. Through the identification of chemopreventive agents that inhibit or reverse the process of carcinogenesis, new strategies of early intervention can be developed for patients at high risk that potentially prevent the onset of invasive and metastatic phases of cancer. This articles reviews the present efforts in chemoprevention research, including the identification of promising agents, screening, and preclinical and clinical evaluations.

引用

页码：31 / &

共 75 条

[1]

Sporn MB, Approaches to prevention of epithelial cancer during the preneoplastic period, Cancer Res, 36, pp. 2699-2702, (1976)

[2]

Lippman SM, Hittelman WN, Lotan R, Et al., Recent advances in cancer chemoprevention, Cancer Cells, 3, pp. 59-65, (1991)

[3]

Wattenberg LW, Chemoprevention of cancer, Cancer Res, 45, pp. 1-8, (1985)

[4]

Sporn MB, Carcinogenesis and cancer: Different perspectives on the same disease, Cancer Res, 51, pp. 6215-6218, (1991)

[5]

Weinstein IB, Cancer prevention: Recent progress and future opportunities, Cancer Res, 51, pp. 5080s-5085s, (1991)

[6]

Henderson BE, Ross RK, Pike MC, Casagrande JT, Endogenous hormones as a major factor in human cancer, Cancer Res, 42, pp. 3232-3239, (1982)

[7]

Henderson BE, Ross R, Bernstein L, Estrogens as a cause of human cancer: The Richard and Hinda Rosenthal Foundation Award Lecture, Cancer Res, 48, pp. 246-253, (1988)

[8]

Wattenberg LW, Inhibition of chemical carcinogenesis, J Natl Cancer Inst, 60, pp. 11-18, (1978)

[9]

Garewal HS, Meyskens FL, Chemoprevention of cancer, Hematol Oncol Clin North Am, 5, pp. 69-77, (1991)

[10]

Wattenberg LW, Inhibition of carcinogenesis by minor anutrient constituents of the diet, Proc Nutr Soc, 49, pp. 173-183, (1990)

← 1 2 3 4 5 6 7 8 →