Cocaine-induced changes in time course of regional cerebral blood volume and transit time as determined by dynamic MR imaging

被引：5

作者：

Li, KL ^{[1
]}

Suojanen, JN ^{[1
]}

机构：

[1] HARVARD UNIV,DEACONESS HOSP,DEPT RADIOL SCI,BOSTON,MA 02215

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1995年 / 5卷 / 06期

关键词：

cocaine; regional cerebral blood volume; mean transit time; functional MR imaging;

D O I：

10.1002/jmri.1880050616

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We examined cocaine-mediated changes in regional cerebral blood volume (rCBV) and mean transit time (MTT) in central brain structures of rats using functional MR imaging techniques. Changes in MTT and rCBV in animals who had previously been given cocaine depended on the length of time between the last pretreatment injection and the acute injection and seemed to parallel cocaine-mediated changes in extracellular dopamine concentrations.

引用

页码：715 / 718

页数：4

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