METABOLISM OF BENZO(A)PYRENE, 7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE AND 9,10-DIHYDRO-9,10-DIHYDROXYBENZO(A)PYRENE BY SHORT-TERM ORGAN-CULTURES OF HAMSTER LUNG

被引：32

作者：

COHEN, GM ^{[1
]}

MOORE, BP ^{[1
]}

机构：

[1] UNIV SURREY, DEPT BIOCHEM, GUILDFORD GU2 5XH, SURREY, ENGLAND

来源：

BIOCHEMICAL PHARMACOLOGY | 1977年 / 26卷 / 16期

关键词：

D O I：

10.1016/0006-2952(77)90419-1

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1481 / 1487

页数：7

共 27 条

[1] DIFFERENT PATHWAYS INVOLVED IN METABOLISM OF 7,8-DIHYDRODIOLS AND 9,10-DIHYDRODIOLS OF BENZO(A)PYRENE [J].

BOOTH, J ;

SIMS, P .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (08) :979-980

[2] METABOLIC CONVERSION OF BENZO[ALPHA]PYRENE BY SYRIAN-HAMSTER LIVER-MICROSOMES AND BINDING OF METABOLITES TO DEOXYRIBONUCLEIC ACID [J].

BORGEN, A ;

DARVEY, H ;

CASTAGNO.N ;

CROCKER, TT ;

RASMUSSE.RE ;

WANG, IY .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (05) :502-506

[3] METABOLISM OF [BENZO(A)PYRENE-H-3 BY DIFFERENT PORTIONS OF RESPIRATORY-TRACT [J].

COHEN, GM ;

MOORE, BP .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (14) :1623-1629

[4] BENZO(A)PYREN-3-YL HYDROGEN SULFATE, A MAJOR ETHYL ACETATE-EXTRACTABLE METABOLITE OF BENZO(A)PYRENE IN HUMAN, HAMSTER AND RAT LUNG CULTURES [J].

COHEN, GM ;

HAWS, SM ;

MOORE, BP ;

BRIDGES, JW .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (23) :2561-2570

[5] FLUORESCENCE SPECTRAL EVIDENCE THAT BENZO(A)PYRENE-DNA PRODUCTS IN MOUSE SKIN ARISE FROM DIOL-EPOXIDES [J].

DAUDEL, P ;

DUQUESNE, M ;

VIGNY, P ;

GROVER, PL ;

SIMS, P .

FEBS LETTERS, 1975, 57 (03) :250-253

[6] RELIABLE, SENSITIVE, AND CONVENIENT RADIOACTIVE ASSAY FOR BENZPYRENE MONOOXYGENASE [J].

DEPIERRE, JW ;

MORON, MS ;

JOHANNESEN, KA ;

ERNSTER, L .

ANALYTICAL BIOCHEMISTRY, 1975, 63 (02) :470-484

[7] METABOLISM OF POLYCYCLIC-HYDROCARBONS BY RAT LUNG PREPARATIONS [J].

GROVER, PL ;

HEWER, A ;

SIMS, P .

BIOCHEMICAL PHARMACOLOGY, 1974, 23 (02) :323-332

[8] IN-VITRO TRANSFORMATION OF RODENT CELLS BY K-REGION DERIVATIVES OF POLYCYCLIC HYDROCARBONS (TISSUE CULTURE/EPOXIDES/CARCINOGENS/DIOLS/PHENOLS) [J].

GROVER, PL ;

SIMS, P ;

HUBERMAN, E ;

MARQUARDT, H ;

KUROKI, T ;

HEIDELBERGER, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1971, 68 (06) :1098-+

[9] INVOLVEMENT OF A DIOL-EPOXIDE IN METABOLIC ACTIVATION OF BENZO(A)PYRENE IN HUMAN BRONCHIAL-MUCOSA AND IN MOUSE SKIN [J].

GROVER, PL ;

HEWER, A ;

PAL, K ;

SIMS, P .

INTERNATIONAL JOURNAL OF CANCER, 1976, 18 (01) :1-6

[10] CHEMICAL CARCINOGENESIS [J].

HEIDELBERGER, C .

ANNUAL REVIEW OF BIOCHEMISTRY, 1975, 44 :79-121

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