EPITHELIAL OR DANDRUFF ALLERGEN FOR THE DIAGNOSIS OF DOG ALLERGY BY RAST

被引:7
作者
MERRETT, TG
MERRETT, J
机构
[1] RAST Allergy Unit, Benenden Chest Hospital, Cranbrook, Kent
来源
CLINICAL ALLERGY | 1979年 / 9卷 / 05期
关键词
D O I
10.1111/j.1365-2222.1979.tb02505.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
When used for screening by the RAST technique, dog epithelium provided too few positive results (29.2%) compared with dog dandruff (58.8%), cat epithelium (53.6%) and horse dandruff (52.2%). However, dog dandruff can provide an unexpectedly high incidence of positive RAST results (45.2%) in sera from patients with an allergic history to cat or horse, but not to dog. Dog dandruff allergens were found to cross‐react with some cat or horse serum proteins in about 25% of such patients. We conclude that dog dandruff is preferable to epithelium for screening by the RAST technique, but if emotional issues involving a family pet arise then confirmation by a trial separation is likely to be more convincing than a provocation test with a possibly non‐specific allergenic extract. Copyright © 1979, Wiley Blackwell. All rights reserved
引用
收藏
页码:429 / 435
页数:7
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