SYNTHESIS OF NEW POLYFUNCTIONALLY SUBSTITUTED PYRIDAZINES, PHTHALAZINES, CINNOLINES AND THIENO[3,4-C]PYRIDAZINES

被引：20

作者：

ELKOUSY, S ^{[1
]}

ELSAKKA, I ^{[1
]}

ELTORGOMAN, AM ^{[1
]}

ROSHDY, H ^{[1
]}

ELNAGDI, MH ^{[1
]}

机构：

[1] UNIV CAIRO,FAC SCI,DEPT CHEM,GIZA,EGYPT

来源：

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1990年 / 55卷 / 12期

关键词：

D O I：

10.1135/cccc19902977

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of ethyl 2-arylhydrazono-3-oxobutyrates (Ia, Ib) with active methylene ketones afforded pyridazin-5-carbonitrile derivatives. The methyl function in the ethyl pyridazin-3-carboxylate derivatives IIa, IIb reacted with arylidenemalononitrile to yield the phthalazine derivatives Va-Vf and with elemental sulphur to yield the thienopyridazines XIXa, XIXb. The cinnolines are producted from reaction of IIa, IIb with diethyl acetonedicarboxylate.

引用

页码：2977 / 2986

页数：10

共 6 条

[1]

ELNAGDI MH, 1988, LIEBIGS ANN CHEM, P909

[2]

ELNAGDI MH, 1989, LIEBIGS ANN CHEM, P1255

[3] STUDIES ON CONDENSED PYRAZOLES - SYNTHESIS OF NEW METHYL AND AMINO PYRAZOLO(1,5-A)PYRIMIDINES AND OF PYRAZOLO(5,1-C)(1,2,4)TRIAZINES [J].

ELNAGDI, MH ;

TAHA, NH ;

ABDEL, F ;

ELALL, MA ;

ABDELMOTALEB, RM ;

MAHMOUD, FF .

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1989, 54 (04) :1082-1091

[4]

ELNAGDI MH, 1988, LIEBIGS ANN CHEM, P1005

[5]

ELNAGDI MH, 1989, TETRAHEDRON, V45, P3604

[6] HETEROCYCLEN AUS CH-ACIDEN NITRILEN .7. 2-AMINO-THIOPHENE AUS ALPHA-OXO-MERCAPTANEN UND METHYLENAKTIVEN NITRILEN [J].

GEWALD, K .

CHEMISCHE BERICHTE-RECUEIL, 1965, 98 (11) :3571-&

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