CLONING AND NUCLEOTIDE-SEQUENCE OF A CHROMOSOMALLY ENCODED TETRACYCLINE RESISTANCE DETERMINANT, TETA(M), FROM A PATHOGENIC, METHICILLIN-RESISTANT STRAIN OF STAPHYLOCOCCUS-AUREUS

被引：60

作者：

NESIN, M

SVEC, P

LUPSKI, JR

GODSON, GN

KREISWIRTH, B

KORNBLUM, J

PROJAN, SJ

机构：

[1] PUBL HLTH RES INST CITY NEW YORK INC,DEPT APPL BIOL,455 1ST AVE,NEW YORK,NY 10016

[2] PUBL HLTH RES INST CITY NEW YORK INC,DEPT PLASMID BIOL,NEW YORK,NY 10016

[3] NYU MED CTR,DEPT BIOCHEM,NEW YORK,NY 10016

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1990年 / 34卷 / 11期

关键词：

D O I：

10.1128/AAC.34.11.2273

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This report describes the cloning and sequencing of a chromosomally encoded tetracycline resistance determinant from a clinical isolate of methicillin-resistant Staphylococcus aureus. On the basis of the sequence, the gene is in the tet(M) class, and it was shown that the S. aureus tetA(M) gene is induced at the level of transcription.

引用

页码：2273 / 2276

页数：4

共 21 条

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