THE REPRODUCTIVE LIFE-SPAN OF ONCHOCERCA-VOLVULUS IN WEST AFRICAN SAVANNA

被引：129

作者：

PLAISIER, AP ^{[1
]}

VANOORTMARSSEN, GJ ^{[1
]}

REMME, J ^{[1
]}

HABBEMA, JDF ^{[1
]}

机构：

[1] ONCHOCERCIASIS CONTROL PROGRAM,OUAGADOUGOU,BURKINA FASO

来源：

ACTA TROPICA | 1991年 / 48卷 / 04期

关键词：

ONCHOCERCA-VOLVULUS; ONCHOCERCIASIS; PARASITE LIFE-SPAN; SIMULATION MODEL;

D O I：

10.1016/0001-706X(91)90015-C

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The epidemiological model ONCHOSIM - a model and computer simulation program for the transmission and control of onchocerciasis - has been used to determine the range of plausible values for the reproductive lifespan of Onchocerca volvulus. Model predictions based on different lifespan quantifications were compared with the results of longitudinal skin-snip surveys undertaken in 4 reference villages during 13 to 14 years of successful vector control in the Onchocerciasis Control Programme in West Africa. Good fits between predicted and observed trends in skin microfilarial loads could be obtained for all villages. It is concluded that the reproductive lifespan of the savanna strain of O. volvulus lies between 9 and 11 years, and that 95% of the parasites reach the end of reproduction before the age of 13 to 14 years.

引用

页码：271 / 284

页数：14

共 21 条

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