THE CHEMISTRY OF 5-OXODIHYDROISOXAZOLES .4. REACTIONS OF SOME N-ARYLISOXAZOL-5-ONES WITH NUCLEOPHILES

被引：15

作者：

ANG, KH

DONATI, C

DONKOR, A

PRAGER, RH

机构：

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1992年 / 45卷 / 12期

关键词：

D O I：

10.1071/CH9922037

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reactions of ethyl 2-aryl-5-oxo-2,5-dihydroisoxazole-4-carboxylate (aryl = phenyl, isoquinolin-1-yl, 2-phenylquinazolin-4-yl and 5-nitropyridin-2-yl) with azide and primary, secondary and tertiary amines, and a number of other nucleophiles axe described, and the product formation is rationalized in terms of predominant initial attack by the nucleophile at C3, or abstraction of H3, of the isoxazole ring.

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页码：2037 / 2048

页数：12

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