COMPARTMENTALIZATION OF PARVALBUMIN IMMUNOREACTIVITY IN THE HUMAN STRIATUM

被引：40

作者：

WALDVOGEL, HJ

FAULL, RLM

机构：

[1] Department of Anatomy, School of Medicine, The University of Auckland, Auckland

来源：

BRAIN RESEARCH | 1993年 / 610卷 / 02期

关键词：

HUMAN; STRIATUM; PARVALBUMIN; IMMUNOHISTOCHEMISTRY; NEUROCHEMICAL COMPARTMENT;

D O I：

10.1016/0006-8993(93)91415-O

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The distribution of parvalbumin in the basal ganglia was studied in eight human brains using immunohistochemical techniques and the pattern of staining was compared to the distribution of enkephalin immunoreactivity in adjacent sections. The results showed a heterogeneous pattern of parvalbumin immunoreactivity in the caudate nucleus and putamen; this pattern of staining was characterized by irregularly shaped patches of low parvalbumin immunoreactivity dispersed against a background matrix of moderate-to-high immunoreactive staining. These parvalbumin-poor patches in the caudate nucleus and putamen aligned with the enkephalin-rich striosomes. These results show that parvalbumin immunoreactivity in the human striatum has the same compartmental mosaic organization as other neurochemical markers in the mammalian striatum.

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页码：311 / 316

页数：6

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