WARFARIN TREATMENT OF MICE BEARING AUTOCHTHONOUS TUMORS - EFFECT ON SPONTANEOUS METASTASES

被引：53

作者：

RYAN, JJ

KETCHAM, AS

WEXLER, H

机构：

[1] National Cancer Institute, Bethesda

来源：

SCIENCE | 1968年 / 162卷 / 3861期

关键词：

D O I：

10.1126/science.162.3861.1493

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Long-term oral administration of sodium warfarin significantly reduced the incidence of spontaneous metastases in the lungs from 83 percent in controls to 8 percent in treated C57/BL/6N mice. The size and weight of primary tumors in mice treated with warfarin were less than in control mice. Length of survival was unaffected.

引用

页码：1493 / &