DNA REPLICATION STUDIES OF HUMAN D-GROUP CHROMOSOMES IN SATELLITE ASSOCIATIONS

被引:32
作者
NAKAGOME, Y
机构
[1] Division of Teratology Children’s Hospital Research Foundation, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati
来源
CYTOGENETICS | 1969年 / 8卷 / 04期
关键词
D O I
10.1159/000130040
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
DNA replication studies were carried out on metaphase plates showing satellite associations to determine the association of individual D chromosomes. In a total of 279 D chromosomes involved in satellite associations and identified by autoradiography, it was found that the association of the three members of the D chromosomes was random. In D/D associations no prevalence of homologous combination was observed. In addition, a case of Dtrisomy and three cases with t(GqDq) (from two unrelated families) were studied. The extra D chromosome in the first case was identified as a No. 13 by the labelling pattern. In the other three cases, the D chromosome involved in the translocation was identified as a No. 14. Studies of satellite associations in these cases are also described. © 1969 S. Karger AG, Basel.
引用
收藏
页码:296 / +
页数:1
相关论文
共 27 条
[1]  
ABBO G, 1966, HELV PAEDIATR ACTA, V21, P293
[2]  
BLOOM GE, 1968, SOC PEDIAT RES ATLAN
[3]  
BLOOM GE, 1967, AMER SOC HUM GENET T
[4]   TRISOMY D1 WITH 2 D/D TRANSLOCATION CHROMOSOMES - REPORT OF A CASE [J].
COHEN, MM ;
TAKAGI, N ;
HARROD, EK .
AMERICAN JOURNAL OF DISEASES OF CHILDREN, 1968, 115 (02) :185-&
[5]   ASSOCIATION OF ACROCENTRIC CHROMOSOMES IN 1000 NORMAL HUMAN MALE METAPHASE CELLS [J].
COHEN, MM ;
SHAW, MW .
ANNALS OF HUMAN GENETICS, 1967, 31 :129-+
[6]  
DEKABAN AS, 1966, AM J HUM GENET, V18, P288
[7]  
ENGMANN FR, 1967, LANCET, V2, P1114
[8]   OBSERVATIONS ON SATELLITED HUMAN CHROMOSOMES [J].
FERGUS.MA ;
HANDMAKER, SD .
LANCET, 1961, 1 (717) :638-+
[9]  
FERGUSON-SMITH M. A., 1964, CYTOGENETICS, V3, P124, DOI 10.1159/000129803
[10]  
FORD EHR, 1967, LANCET, V2, P26