RELEVANCE OF INVITRO SYNERGY TO THERAPY - DOES SYNERGY BETWEEN DIAMINOPYRIMIDINES AND SULFONAMIDES OPERATE AT CONCENTRATIONS ACHIEVABLE IN URINE

被引:16
作者
GREENWOOD, D
机构
[1] Department of Microbiology, University Hospital, Queen’s Medical Centre, Nottingham
关键词
D O I
10.1093/jac/5.Supplement_B.85
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The interaction between trimethoprim and sulphamethoxazole was investigated in an in vitro model of the urinary bladder. At concentrations well within those achievable in urine using conventional therapeutic regimens, the additional presence of sulphamethoxazole contributed nothing to the dominant activity of trimethoprim. © 1979 Oxford University Press.
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页码:85 / 89
页数:5
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