NEW RADICAL-MEDIATED POLYOLEFIN CYCLIZATIONS DIRECTED TOWARDS STEROID RING SYNTHESIS

被引:51
作者
CHEN, LG [1 ]
GILL, GB [1 ]
PATTENDEN, G [1 ]
机构
[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND
关键词
D O I
10.1016/S0040-4039(00)77180-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Treatment of appropriately substituted 5,9-diene, 5,9,13-triene and 5,9,13,17-tetraene phenoselenyl esters, e.g. 1a, 9 and 14, with Bu(3)SnH-AIBN is shown to lead to linear and angular six-ring fused polycycles, viz 2, 11 and 15 respectively, via consecutive 6-endo-trig modes of cyclisations starting from the corresponding polyolefin acyl radical intermediates.
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页码:2593 / 2596
页数:4
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