EVALUATION OF AN ACTBP2 LADDER COMPOSED OF 26 SEQUENCED ALLELES

被引：35

作者：

MOLLER, A ^{[1
]}

SCHURENKAMP, M ^{[1
]}

BRINKMANN, B ^{[1
]}

机构：

[1] UNIV MUNSTER,INST LEGAL MED,D-48149 MUNSTER,GERMANY

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1995年 / 108卷 / 02期

关键词：

STR SYSTEM ACTBP2; SEQUENCING; SEQUENCE VARIATION; ALLELIC LADDER; VALIDATION STUDY;

D O I：

10.1007/BF01369908

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A total of 90 alleles found in white Caucasians from North-West Germany were sequenced and 26 alleles chosen to construct a uniform and reliable allelic ladder for the STR system ACTBP2 (SE33). Ln addition 3 new aspects concerning the sequence structure were observed. Population studies were carried out on white Caucasians (n = 278) from North-West Germany using the new improved ladder. A total of 24 alleles and 14 ''interalleles'' were found and reproducible results obtained. No significant deviation from Hardy-Weinberg-equilibrium could be observed.

引用

页码：75 / 78

页数：4

共 13 条

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