FLAGELLAR ASSEMBLY IN 250 EASY-TO-FOLLOW STEPS

被引：174

作者：

DUTCHER, SK

机构：

[1] Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder

来源：

TRENDS IN GENETICS | 1995年 / 11卷 / 10期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/S0168-9525(00)89123-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The eukaryotic flagellum is a complex biochemical machine that moves cells or moves materials over the surface of cells, such as in the mammalian esophagus, oviduct or in protozoa. It is composed of over 250 polypeptides that must be assembled into a number of different structures and each structure must be attached with an exact periodicity along the microtubules. Once the flagellum is assembled, each of the components must act in concert and in three dimensions to produce a complex waveform. This review provides an outline of the composition and function of the different structures found in the flagella of Chlamydomonas.

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页码：398 / 404

页数：7

相关论文

共 62 条

[1] CENTRAL-PAIR MICROTUBULAR COMPLEX OF CHLAMYDOMONAS FLAGELLA - POLYPEPTIDE COMPOSITION AS REVEALED BY ANALYSIS OF MUTANTS [J].

ADAMS, GMW ;

HUANG, B ;

PIPERNO, G ;

LUCK, DJL .

JOURNAL OF CELL BIOLOGY, 1981, 91 (01) :69-76

[2] A NEW KINESIN-LIKE PROTEIN (KLP1) LOCALIZED TO A SINGLE MICROTUBULE OF THE CHLAMYDOMONAS-FLAGELLUM [J].

BERNSTEIN, M ;

BEECH, PL ;

KATZ, SG ;

ROSENBAUM, JL .

JOURNAL OF CELL BIOLOGY, 1994, 125 (06) :1313-1326

[3] Flagella in prokaryotes and lower eukaryotes [J].

Blair, David F. ;

Dutcher, Susan K. .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1992, 2 (05) :756-767

[4] SEQUENCE-ANALYSIS REVEALS HOMOLOGY BETWEEN 2 PROTEINS OF THE FLAGELLAR RADIAL SPOKE [J].

CURRY, AM ;

WILLIAMS, BD ;

ROSENBAUM, JL .

MOLECULAR AND CELLULAR BIOLOGY, 1992, 12 (09) :3967-3977

[5] FLAGELLAR RADIAL SPOKE - A MODEL MOLECULAR GENETIC SYSTEM FOR STUDYING ORGANELLE ASSEMBLY [J].

CURRY, AM ;

ROSENBAUM, JL .

CELL MOTILITY AND THE CYTOSKELETON, 1993, 24 (04) :224-232

[6] THE ARGININOSUCCINATE LYASE GENE OF CHLAMYDOMONAS-REINHARDTII - AN IMPORTANT TOOL FOR NUCLEAR TRANSFORMATION AND FOR CORRELATING THE GENETIC AND MOLECULAR MAPS OF THE ARG7 LOCUS [J].

DEBUCHY, R ;

PURTON, S ;

ROCHAIX, JD .

EMBO JOURNAL, 1989, 8 (10) :2803-2809

[7] ASSEMBLY OF FLAGELLAR RADIAL SPOKE PROTEINS IN CHLAMYDOMONAS - IDENTIFICATION OF THE AXONEME BINDING DOMAIN OF RADIAL SPOKE PROTEIN-3 [J].

DIENER, DR ;

ANG, LH ;

ROSENBAUM, JL .

JOURNAL OF CELL BIOLOGY, 1993, 123 (01) :183-190

[8] RESCUE OF A PARALYZED-FLAGELLA MUTANT OF CHLAMYDOMONAS BY TRANSFORMATION [J].

DIENER, DR ;

CURRY, AM ;

JOHNSON, KA ;

WILLIAMS, BD ;

LEFEBVRE, PA ;

KINDLE, KL ;

ROSENBAUM, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (15) :5739-5743

[9] GENETIC DISSECTION OF THE CENTRAL PAIR MICROTUBULES OF THE FLAGELLA OF CHLAMYDOMONAS-REINHARDTII [J].

DUTCHER, SK ;

HUANG, B ;

LUCK, DJL .

JOURNAL OF CELL BIOLOGY, 1984, 98 (01) :229-236

[10]

FOX LA, 1994, J CELL SCI, V107, P1545

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