SOME ELECTRONIC FACTORS IN DRUG-RECEPTOR INTERACTIONS

被引：40

作者：

CAMMARAT.A

机构：

[1] Department of Chemistry, Department of Pharmaceutical Chemistry, Medical College of Virginia, Richmond

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1968年 / 11卷 / 06期

关键词：

D O I：

10.1021/jm00312a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Many of the physicochemical approaches to the study of drug action are shown to be interrelated. The principle of hard and soft acids and bases, in its quantitative form, is indicated as applying to drug action. © 1968, American Chemical Society. All rights reserved.

引用

页码：1111 / &

共 27 条

[1] ARIENS EJ, 1964, MOL PHARMACOL, V1, P136
[2] BARROW GM, 1966, PHYSICAL CHEMISTRY
[3] ASPECTS OF CHEMICAL MECHANISM OF COMPLEX FORMATION BETWEEN ACETYLCHOLINESTERASE + ACETYLCHOLINE-RELATED COMPOUNDS
BELLEAU, B
LACASSE, G
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1964, 7 (06) : 768 - &
[4] MOLECULAR THEORY OF DRUG ACTION BASED ON INDUCED CONFORMATIONAL PERTURBATIONS OF RECEPTORS
BELLEAU, B
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1964, 7 (06) : 776 - &
[5] BLOOM BM, 1966, ADV DRUG RES, V3, P121
[6] CAIN CK, 1967, ANNUAL REVIEW MED ED
[7] MOLECULAR ORBITAL METHODS IN STUDY OF CHOLINESTERASE INHIBITORS
CAMMARAT.A
STEIN, RL
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (04) : 829 - &
[8] CAMMARATA A, UNPUBLISHED RESULTS
[9] MATHEMATICAL CONTRIBUTION TO STRUCTURE-ACTIVITY STUDIES
FREE, SM
WILSON, JW
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1964, 7 (04) : 395 - &
[10] NEW SUBSTITUENT CONSTANT PI DERIVED FROM PARTITION COEFFICIENTS
FUJITA, T
HANSCH, C
IWASA, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (23) : 5175 - &

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