REGIONAL DIFFERENCES IN SENSITIVITY OF VESTIBULAR SENSORY EPITHELIA TO OTOTOXIC ANTIBIOTICS

被引:142
作者
LINDEMAN, HH
机构
[1] Otolaryngological Department, University of Gothenburg, Gothenburg
[2] Kir. klin., Lasarettet, Säffle
关键词
D O I
10.3109/00016486909125441
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The effect of intratympanic application of streptomycin and parenteral injections of kanamycin upon the vestibular sensory epithelia have been studied with the surface specimen technique. Clear regional differences in vulnerability to these ototoxic antibiotics have been noticed. The sensory epithelia of the cristae ampullares were more vulnerable than the macula utriculi, which in turn was distinctly more vulnerable than the macula sacculi. The degenerative changes involved primarily the central parts of the crista epithelium and the striola of the maculae. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
收藏
页码:177 / &
相关论文
共 20 条
  • [1] Andersson A., 1966, STRUCTURAL PATTERN O
  • [2] BECK C, 1962, Arch Ohren Nasen Kehlkopfheilkd, V179, P594, DOI 10.1007/BF02103628
  • [3] BERG K, 1949, ANN OTO RHINOL LARYN, V58, P448
  • [4] BERG K, 1951, ACTA OTOLARYNG S S97
  • [5] CAUSSE R, 1949, ANN OTO LARYNG PARIS, V66, P518
  • [6] DUVALL A J, 1964, Acta Otolaryngol, V57, P581, DOI 10.3109/00016486409137120
  • [7] THE OTOTOXICITY OF STREPTOMYCIN
    HAWKINS, JE
    LURIE, MH
    [J]. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1952, 61 (03) : 789 - 809
  • [8] HAWKINS JE, 1964, ACTA OTOLARYNGS S188
  • [9] IGARASHI M, 1966, ACTA OTOLARYNG S214
  • [10] IGARASHI M, 1965, SP77 NASA, P373