EFFECT OF PLATELET DERIVED GROWTH-FACTOR ON HETEROTOPIC BONE-FORMATION IN RATS

被引：11

作者：

RISTO, O ^{[1
]}

WAHLSTROM, O ^{[1
]}

ABDIU, A ^{[1
]}

WALZ, T ^{[1
]}

机构：

[1] LINKOPING UNIV HOSP,DEPT CELL BIOL,S-58185 LINKOPING,SWEDEN

来源：

ACTA ORTHOPAEDICA SCANDINAVICA | 1991年 / 62卷 / 01期

关键词：

D O I：

10.3109/17453679108993090

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Platelet derived growth factor (PDGF) and induction of newly woven bone growth were studied in rats. PDGF (20 ng/mL) was administered continuously for 2 weeks via microosmotic pumps to 6-mm-long pieces of demineralized rat femur inserted into muscle pouches. Each rat had a control piece of demineralized bone inserted into the contralateral gluteal muscle. The samples were collected after 4 weeks, and wet and ash weight were recorded. Fourteen rats were evaluated. There were no differences as regards wet weights. PDGF increased the ash weights.

引用

页码：49 / 51

页数：3

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