SYNTHESIS OF DELTA-L-ALPHA-AMINOADIPOYL-L-CYSTEINYL-D-ALLYLGLYCINE, AND 8 DEUTERATED ANALOGS, SUBSTRATES FOR THE INVESTIGATION OF THE MECHANISM OF ACTION OF ISOPENICILLIN-N SYNTHASE

被引：14

作者：

BALDWIN, JE ^{[1
]}

BRADLEY, M ^{[1
]}

TURNER, NJ ^{[1
]}

ADLINGTON, RM ^{[1
]}

PITT, AR ^{[1
]}

SHERIDAN, H ^{[1
]}

机构：

[1] UNIV OXFORD,OXFORD CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND

来源：

TETRAHEDRON | 1991年 / 47卷 / 38期

关键词：

D O I：

10.1016/S0040-4020(01)91015-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of delta-L-alpha-aminoadipoyl-L-cysteinyl-D-allylglycine (1a) from its component amino acids is described, along with the synthesis of eight analogues (1b-i) specifically deuterated at C-3 and/or C-5 of the allylglycine residue.

引用

页码：8203 / 8222

页数：20

共 24 条

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