CATABOLISM OF 3-HYDROXYPHENYLACETIC AND 4-HYDROXYPHENYLACETIC ACID BY KLEBSIELLA-PNEUMONIAE

被引：33

作者：

MARTIN, M ^{[1
]}

GIBELLO, A ^{[1
]}

FERNANDEZ, J ^{[1
]}

FERRER, E ^{[1
]}

GARRIDOPERTIERRA, A ^{[1
]}

机构：

[1] UNIV COMPLUTENSE MADRID,DEPT MICROBIOL PATOL ANIM 1,E-28040 MADRID,SPAIN

来源：

JOURNAL OF GENERAL MICROBIOLOGY | 1991年 / 137卷

关键词：

D O I：

10.1099/00221287-137-3-621

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Klebsiella pneumoniae catabolizes both 4-hydroxyphenylacetic acid and 3-hydroxyphenylacetic acid via metacleavage of 3,4-dihydroxyphenylacetic acid, ultimately yielding pyruvate and succinate. The organism can synthesize two hydroxylases catalysing 3,4-dihydroxyphenylacetic acid formation, which differ in substrate specificity, cofactor requirement, kinetics and regulation. Five enzymes sequentially involved in the catabolism of 3,4-dihydroxyphenylacetic acid are encoded on a 7 kbp fragment of the K. pneumoniae chromosome that has been isolated in a recombinant plasmid.

引用

页码：621 / 628

页数：8

共 23 条

[1] METABOLISM OF P-HYDROXYPHENYLACETIC ACID IN PSEUDOMONAS OVALIS [J].

ADACHI, K ;

SENOH, S ;

TAKEDA, Y ;

KITA, H .

BIOCHIMICA ET BIOPHYSICA ACTA, 1964, 93 (03) :483-&

[2] CARBOXYMETHYLHYDROXYMUCONIC SEMI-ALDEHYDE DEHYDROGENASE IN THE 4-HYDROXYPHENYLACETATE CATABOLIC PATHWAY OF ESCHERICHIA-COLI [J].

ALONSO, JM ;

GARRIDOPERTIERRA, A .

BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 719 (01) :165-167

[3] CATABOLISM OF AROMATIC-ACIDS IN TRICHOSPORON-CUTANEUM [J].

ANDERSON, JJ ;

DAGLEY, S .

JOURNAL OF BACTERIOLOGY, 1980, 141 (02) :534-543

[4] MICROBIAL CONVERSION OF PARA HYDROXYPHENYLACETIC ACID TO HOMOGENTISIC ACID [J].

BLAKLEY, ER .

CANADIAN JOURNAL OF MICROBIOLOGY, 1972, 18 (08) :1247-&

[5]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[6] ELECTRON-MICROSCOPIC CHARACTERIZATION OF DNAS OF NON-DEFECTIVE DELETION MUTANTS OF BACTERIOPHAGE-MU [J].

CHOW, LT ;

KAHMANN, R ;

KAMP, D .

JOURNAL OF MOLECULAR BIOLOGY, 1977, 113 (04) :591-609

[7]

COOPERRA, 1980, J BACTEROLOGY, V143, P30

[8]

FAWCETT T, 1989, FEMS MICROBIOL LETT, V57, P307

[9]

FERRER E, 1988, FEMS MICROBIOL LETT, V52, P155

[10]

GARRIDOPERTIERRA A, 1981, EUR J BIOCHEM, V117, P581

← 1 2 3 →