NITRONE CYCLOADDITION-BASED ENTRY TO THE COCCINELLINE ALKALOID SKELETON - SYNTHESIS OF (+/-)-EPI-HIPPODAMINE

被引：13

作者：

ADAMS, DR ^{[1
]}

CARRUTHERS, W ^{[1
]}

CROWLEY, PJ ^{[1
]}

机构：

[1] ICI AGROCHEM,JEALOTTS HILL RES STN,BRACKNELL RG12 6EY,BERKS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 18期

关键词：

D O I：

10.1039/c39910001261

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthesis of intermediate 13 possessing the perhydropyrido[2,1,6-de]quinolizine skeleton of the coccinelline alkaloids and conversion to epi-hippodamine 20 was accomplished with stereochemical control arising from a key cycloaddition reaction of nitrone 2 with ethyl hexa-3,5-dienoate.

引用

页码：1261 / 1263

页数：3

共 20 条

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