CEPHALIC PYODERMA-GANGRENOSUM (PG)-LIKE LESIONS AS A PRESENTING SIGN OF WEGENERS GRANULOMATOSIS

被引:18
作者
MICALI, G
COOK, B
RONAN, S
YADGIR, J
SOLOMON, LM
机构
[1] UNIV ILLINOIS,MED CTR,ABRAHAM LINCOLN SCH MED,DEPT DERMATOL,CHICAGO,IL 60612
[2] UNIV ILLINOIS,MED CTR,ABRAHAM LINCOLN SCH MED,DEPT PATHOL,CHICAGO,IL 60612
关键词
D O I
10.1111/j.1365-4362.1994.tb02858.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background. Pyoderma gangrenosum (PG)-like lesions can be associated with Wegener's granulomatosis (WG); in rare instances, they could be the presenting sign of WG. The purpose of this study was to elucidate the relationship between these two disorders. Methods. The clinical and histologic data from a case of WG with primary ulcerative lesions of the face were compared with five other cases previously reported in the literature. Results. A predominance among young men was noted. in three patients the histology of the skin ulcerations was suggestive of WG, in the remaining three, including the case described, it was nonspecific. Two cases developed pulmonary WG after the skin lesions cleared, showing that the extent and severity of skin lesions do not necessarily correlate with the systemic disease. Conclusions. When the histology of the skin is nonspecific, the diagnosis of PG or PG-like lesions of the head and neck should not be considered definitive and the patients should be carefully monitored to rule out the possible presence of WG.
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收藏
页码:477 / 480
页数:4
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