DEVELOPMENT OF RECEPTORS FOR ALPHA-BUNGAROTOXIN IN CHICK-EMBRYO SYMPATHETIC-GANGLION NEURONS INVITRO

被引：12

作者：

DVORAK, D

GIPPS, E

LEAH, J

KIDSON, C

机构：

[1] Department of Biochemistry University of Queensland, Brisbane

来源：

LIFE SCIENCES | 1978年 / 22卷 / 05期

关键词：

D O I：

10.1016/0024-3205(78)90287-4

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The development of receptors for α-bungarotoxin was examined in neurons in dissociated cultures of cells derived from chick embryo sympathetic ganglia. Neurons from 12 day embryos showed a marked increase in receptor numbers per cell over 3-4 days in culture. The increase was less marked in neurons from 14 day embryos and absent in 19 day embryos. The incidence of cholinergic synapses in cultures from 12 day and 19 day embryos was also examined. Evidence for synapse formation was found only in cultures from older embryos. © 1978.

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页码：407 / 414

页数：8

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