Scientific Opinion in relation to the authorisation procedure for health claims on calcium and vitamin D and the reduction of the risk of osteoporotic fractures by reducing bone loss pursuant to Article 14 of Regulation (EC) No 1924/2006

被引：7

作者：

Agostoni, Carlo ^{[1
]}

Bresson, Jean-Louis ^{[1
]}

Fairweather-Tait, Susan ^{[1
]}

Flynn, Albert ^{[1
]}

Golly, Ines ^{[1
]}

Korhonen, Hannu ^{[1
]}

Lagiou, Pagona ^{[1
]}

Lovik, Martinus ^{[1
]}

Marchelli, Rosangela ^{[1
]}

Martin, Ambroise ^{[1
]}

Moseley, Bevan ^{[1
]}

Neuhaeuser-Berthold, Monika ^{[1
]}

Przyrembel, Hildegard ^{[1
]}

Salminen, Seppo ^{[1
]}

Sanz, Yolanda ^{[1
]}

Strain, Sean ^{[1
]}

Strobel, Stephan ^{[1
]}

Tetens, Inge ^{[1
]}

Tome, Daniel ^{[1
]}

van Loveren, Hendrik ^{[1
]}

Verhagen, Hans ^{[1
]}

机构：

[1] EFSA, Parma, Italy

来源：

EFSA JOURNAL | 2010年 / 8卷 / 05期

关键词：

Calcium; vitamin D; cholecalciferol; osteoporosis; bone mineral density; osteoporotic fractures; health claims;

D O I：

10.2903/j.efsa.2010.1609

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver a scientific opinion in relation to the authorisation procedure for health claims on calcium and vitamin D and the reduction of the risk of osteoporotic fractures by reducing bone loss pursuant to Article 14 of Regulation (EC) No 1924/2006. A cause and effect relationship was established between the intake of calcium, either alone or in combination with vitamin D, and reducing the loss of BMD, which may contribute to a reduction in the risk of bone fracture. This relationship implies that the critical nutrient in relation to the claimed effect is calcium. The Panel proposes that at least 1200 mg of calcium from all sources or at least 1200 mg of calcium and 800 I. U. of vitamin D from all sources to be consumed daily should be considered for the purpose of setting conditions of use for a risk reduction claim on the loss of BMD, which may contribute to a reduction in the risk of bone fracture. The target population is women 50 years and older. Tolerable Upper Intake Levels (UL) have been established for calcium and vitamin D in adults.

引用

页数：10

共 14 条

[1] Fracture prevention with vitamin D supplementation - A meta-analysis of randomized controlled trials [J].

Bischoff-Ferrari, HA ;

Willett, WC ;

Wong, JB ;

Giovannucci, E ;

Dietrich, T ;

Dawson-Hughes, B .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 293 (18) :2257-2264

[2] Estimation of the dietary requirement for vitamin D in free-living adults ≥64 y of age [J].

Cashman, Kevin D. ;

Wallace, Julie M. W. ;

Horigan, Geraldine ;

Hill, Tom R. ;

Barnes, Maria S. ;

Lucey, Alice J. ;

Bonham, Maxine P. ;

Taylor, Nicola ;

Duffy, Emeir M. ;

Seamans, Kelly ;

Muldowney, Siobhan ;

FitzGerald, Anthony P. ;

Flynn, Albert ;

Strain, J. J. ;

Kiely, Mairead .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2009, 89 (05) :1366-1374

[3]

Chung M, 2009, AHRQ PUBLICATION

[4]

Cranney A., 2007, AHRQ PUBLICATION, V07- E013

[5] A CONTROLLED TRIAL OF THE EFFECT OF CALCIUM SUPPLEMENTATION ON BONE-DENSITY IN POSTMENOPAUSAL WOMEN [J].

DAWSONHUGHES, B ;

DALLAL, GE ;

KRALL, EA ;

SADOWSKI, L ;

SAHYOUN, N ;

TANNENBAUM, S .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (13) :878-883

[6]

European Food Safety Authority (EFSA), 2009, EFSA J, V1180, P1, DOI [10.2903/j.efsa.2009.1180, DOI 10.2903/J.EFSA.2009.1180]

[7]

IOM (Institute of Medicine), 1997, DIET REF INT CALC PH

[8]

SCF (Scientific Committee on Food), 2003, OP SCI COMM FOOD TOL

[9]

SCF (Scientific Committee on Food), 2002, OP SCI COMM FOOD TOL

[10]

SCF (Scientific Committee on Food), 1993, REP NUTR EN INT EUR, P132

← 1 2 →