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ISOLATION IDENTIFICATION AND PROPERTIES OF ISOCHORISMIC ACID . AN INTERMEDIATE IN BIOSYNTHESIS OF 2,3-DIHYDROXYBENZOIC ACID

被引：75
作者：
YOUNG, IG
BATTERHAM, TJ
GIBSON, F
机构：
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 177卷 / 03期
关键词：
D O I：
10.1016/0304-4165(69)90301-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new intermediate in the biosynthesis of 2,3-dihydroxybenzoic acid in Aerobacter aerogenes has been isolated and identified as 2-hydroxy-3-(1′-carboxyvinyloxy)-2,3-dihydrobenzoic acid for which the trivial name isochorismic acid is suggested. Methods for the assay of isochorismic acid are described. Salicylic acid and 3-carboxyphenylpyruvic acid are readily produced chemically from isochorismic acid under mild conditions. It is suggested that isochorismic acid may be the metabolic precursor of these compounds in other organisms. © 1969.
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页码：389 / +
页数：1
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