MECHANISTIC AND STRUCTURAL COMPLEXITY IN THE SITE-SPECIFIC RECOMBINATION PATHWAYS OF INT AND FLP

被引：85

作者：

LANDY, A ^{[1
]}

机构：

[1] BROWN UNIV, PROVIDENCE, RI 02912 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(05)80086-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

This review focuses on two of the approximately 30 members of the diverse Int family of site-specific recombinases. The lambda recombination system represents those reactions involving accessory proteins and a complex higher-order structure. The FLP system represents the most streamlined reactions and has been the subject of detailed and informative studies on the mechanisms of DNA cleavage and ligation.

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页码：699 / 707

页数：9

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