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VIRULENCE ADSORBABILITY AND ANTIGENICITY OF FOOT-AND-MOUTH DISEASE VIRUS SELECTED BY ADSORPTION WITH HOMOGENIZED MOUSE KIDNEY

被引：6
作者：
CAMPBELL, CH
机构：
[1] Plum Island Animal Disease Laboratory, Animal Disease and Parasite Research Division, Agricultural Research Service, U.S. Department of Agriculture, Long Island, N.Y., Greenport
来源：
ARCHIV FUR DIE GESAMTE VIRUSFORSCHUNG | 1969年 / 26卷 / 03期
关键词：
D O I：
10.1007/BF01242376
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A small percentage of a stock foot-and-mouth disease virus population was found to be relatively resistant to adsorption with homogenized adult mouse kidney. To select this portion of the population, a series of 10 passages was performed, each passage consisting of adsorption with homogenized kidney and propagation of the unadsorbed virus in bovine kidney cell cultures. The selected virus was relatively resistant to adsorption with mouse kidney and relatively avirulent for adult mice. It was immunogenic in adult mice and seemed to be antigenically the same as the parent virus. This information might possibly be used in selecting viruses for live virus vaccines. © 1969 Springer-Verlag.
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页码：238 / +
页数：1
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