EFFECT OF LEAD NITRATE ON THE TISSUE DISTRIBUTION OF MERCURY IN RATS TREATED WITH METHYLMERCURY CHLORIDE

被引：12

作者：

CONGIU, L ^{[1
]}

CORONGIU, FP ^{[1
]}

DORE, M ^{[1
]}

MONTALDO, C ^{[1
]}

VARGIOLU, S ^{[1
]}

CASULA, D ^{[1
]}

SPIGA, G ^{[1
]}

机构：

[1] UNIV CAGLIARI,INST OCCUPAT MED,I-09100 CAGLIARI,ITALY

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1979年 / 51卷 / 02期

关键词：

D O I：

10.1016/0041-008X(79)90477-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Tissue concentrations of the reduced form of glutathione in brain, kidney, and liver vary in the same relationship as the tissue concentration of mercury. Brain glutathione is not influenced by lead nitrate administration, but glutathione content of kidney and liver is increased. The administration of lead nitrate which increased kidney glutathione also resulted in increased mercury deposition in the kidney. This provides additional evidence that, in the kidney, glutathione concentrations play a role in control of mercury deposition. © 1979.

引用

页码：363 / 366

页数：4

共 13 条

[1]

ARMSTRONG FAJ, 1971, AT ABSORP NEWSL, V0010, P00101

[2] EFFECT OF SODIUM MALEATE ON RENAL DEPOSITION AND EXCRETION OF MERCURY [J].