PLACENTAL ALKALINE-PHOSPHATASE, ALPHAFETOPROTEIN AND CARCINOEMBRYONIC ANTIGEN IN TESTICULAR-TUMORS - TISSUE TYPING BY MEANS OF CYTOLOGIC SMEARS

被引：97

作者：

WAHREN, B

HOLMGREN, PA

STIGBRAND, T

机构：

[1] NATL BACTERIOL LAB, S-10521 STOCKHOLM, SWEDEN

[2] UMEA UNIV, DEPT PHYSIOL CHEM, S-90185 UMEA, SWEDEN

来源：

INTERNATIONAL JOURNAL OF CANCER | 1979年 / 24卷 / 06期

关键词：

D O I：

10.1002/ijc.2910240608

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Indirect immunofluorescence and radioimmuno‐assay with specific rabbit antisera demonstrated the occurrence of alphafetoprotein (AFP), carcino‐embryonic antigen (CEA) and placental alkaline phosphatase (PLAP) in primary testicular tumor cells. Embryonal carcinomas had AFP‐ and CEA‐containing cells, sometimes PLAP. PLAP and sometimes CEA were found in seminoma cells. Sera from patients with advanced non‐seminomatous tumors could contain any of these antigens or any combination of them. Sera from patients with seminomas had raised PLAP or CEA. PLAP appears to be a new marker for seminoma. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：749 / 753

页数：5

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