LEAD SPECIATION BY HPLC-ICP-AES AND HPLC-ICP-MS

被引：60

作者：

ALRASHDAN, A

HEITKEMPER, D

CARUSO, JA

机构：

[1] Department of Chemistry, University of Cincinnati, Cincinnati, OH

来源：

JOURNAL OF CHROMATOGRAPHIC SCIENCE | 1991年 / 29卷 / 03期

关键词：

D O I：

10.1093/chromsci/29.3.98

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Speciation of inorganic lead (Pb2+) and several trialkyllead species (trimethyllead chloride [TML], triethyllead chloride [TEL], and triphenyllead chloride [TPhL]) is investigated using high-performance liquid chromatography (HPLC) with detection by both inductively coupled plasma emission spectroscopy (ICP-AES), and inductively coupled plasma mass spectrometry (ICP-MS). Reversed-phase, ion-pairing, and ion-exchange HPLC modes are studied. Optimal chromatographic conditions for ICP-AES detection include a reversed-phase separation utilizing a step gradient from 10 to 70% methanol. However, the gradient has been found to destabilize the plasma when using ICP-MS detection. An isocratic separation with a 30% methanol mobile phase has been found to be the best compromise between plasma stability and chromatographic resolution. Detection limits using ICP-MS detection are 3 orders of magnitude improved over ICP-AES detection.

引用

页码：98 / 102

页数：5

共 19 条

[1] AROZA I, 1989, J ANAL ATOM SPECTROM, V4, P167
[2] BEOCKX RL, 1986, ANAL CHEM, V58, pA274
[3] DETERMINATION OF TRIALKYLLEAD SPECIES IN URINE
BLASZKEWICZ, M
BAUMHOER, G
NEIDHART, B
[J]. FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1986, 325 (01): : 129 - 135
[4] COUPLING OF HPLC AND CHEMICAL-REACTION DETECTOR FOR THE SEPARATION AND DETERMINATION OF ORGANOLEAD COMPOUNDS
BLASZKEWICZ, M
BAUMHOER, G
NEIDHART, B
[J]. FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1984, 317 (3-4): : 221 - 225
[5] EXAMINATION OF INTERFERENCES IN THE STRIPPING VOLTAMMETRIC DETERMINATION OF TRIMETHYLLEAD IN SEAWATER BY POLAROGRAPHY AND HG-199 AND PB-207 NUCLEAR MAGNETIC-RESONANCE SPECTROMETRY
BOND, AM
BRADBURY, JR
HANNA, PJ
HOWELL, GN
HUDSON, HA
STROTHER, S
OCONNOR, MJ
[J]. ANALYTICAL CHEMISTRY, 1984, 56 (13) : 2392 - 2396
[6] DETERMINATION OF LEAD IN WHOLE-BLOOD BY ELECTROTHERMAL ATOMIZATION ATOMIC-ABSORPTION SPECTROMETRY USING TUBE AND PLATFORM ATOMIZERS AND DILUTION WITH TRITON X-100
DEBENZO, ZA
FRAILE, R
CARRION, N
LORETO, D
[J]. JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY, 1989, 4 (05) : 397 - 400
[7] DIRECTLY COUPLED CHROMATOGRAPHY - ATOMIC SPECTROSCOPY .2. DIRECTLY COUPLED LIQUID-CHROMATOGRAPHY - ATOMIC SPECTROSCOPY - A REVIEW
EBDON, L
HILL, S
WARD, RW
[J]. ANALYST, 1987, 112 (01) : 1 - 16
[8] DETERMINATION OF ALKYLLEAD SALTS IN WATER AND WHOLE EGGS BY CAPILLARY COLUMN GAS-CHROMATOGRAPHY WITH ELECTRON-CAPTURE DETECTION
FORSYTH, DS
MARSHALL, WD
[J]. ANALYTICAL CHEMISTRY, 1983, 55 (13) : 2132 - 2137
[9] Grandjean P.H., 1984, BIOL EFFECTS ORGANOL
[10] RAPID SPECTROPHOTOMETRIC DETERMINATION OF TRIETHYLLEAD, DIETHYLLEAD, AND INORGANIC LEAD IONS, AND APPLICATION TO DETERMINATION OF TETRAORGGANOLEAD COMPOUNDS
HENDERSON, S
SNYDER, LJ
[J]. ANALYTICAL CHEMISTRY, 1961, 33 (09) : 1172 - &

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