SPECTROPHOTOMETRIC DETERMINATION OF PROMETHAZINE BY FLOW-INJECTION ANALYSIS AND OXIDATION BY CE(IV)

被引：17

作者：

CALATAYUD, JM ^{[1
]}

SANCHO, TG ^{[1
]}

机构：

[1] COLEGIO UNIV CEU,DEPT QUIM,E-46113 MONCADA,SPAIN

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1992年 / 10卷 / 01期

关键词：

FIA; CERIUM(IV); PROMETHAZINE HYDROCHLORIDE; SPECTROPHOTOMETRY;

D O I：

10.1016/0731-7085(92)80008-B

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A flow injection analysis (FIA) procedure is proposed for the determination of promethazine. The sample solution is directly injected into the carrier-reagent stream which comprises a solution of ceric ions in a sulphuric acid medium. The absorbance at 514 nm from the red colour developed by the oxidation of promethazine is measured. Effects of foreign substances have been investigated and the procedure has been applied to the determination of promethazine in a pharmaceutical formulation (tablets).

引用

页码：37 / 42

页数：6

共 16 条

[1]

BERAL H, 1965, ACTA PHARM JUGOSL, V15, P77

[2] COUPLING OF CHROMATOGRAPHIC TECHNIQUES WITH MICRO-INFRARED SPECTROMETRY FOR DETERMINATION OF PHENOTHIAZINE AND RELATED DRUGS [J].