CATALYTIC-HYDROGENATION OF CHIRAL 2-(2-FURYL)-3,4-DIMETHYL-5-PHENYLOXAZOLIDINE

被引：7

作者：

POLYAK, F ^{[1
]}

DOROFEEVA, T ^{[1
]}

ZELCHAN, G ^{[1
]}

机构：

[1] LATVIAN ORGAN SYNTH INST, RIGA 1006, LATVIA

来源：

SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 19期

关键词：

D O I：

10.1080/00397919508011419

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reduction of chiral 2-(2-furyl)-3,4-dimethyl-5-phenyloxazolidines-1,3 by H-2/Raney nickel proceeds simultaneously as hydrogenation of the furan ring and opening of the oxazolidine ring on C2-O bond. Diastereoselectivity in the first reaction was established as ca 40% and 80% depending on the configuration of the oxazolidine 1 and 2.

引用

页码：2895 / 2900

页数：6

共 5 条

[1] ENANTIOSELECTIVE ALKYLATIONS OF GAMMA-OXO ESTERS [J].