NEW DEVELOPMENTS IN ENZYMATIC PEPTIDE-SYNTHESIS

被引：68

作者：

WONG, CH ^{[1
]}

WANG, KT ^{[1
]}

机构：

[1] ACAD SINICA, INST BIOL CHEM, TAIPEI 115, TAIWAN

来源：

EXPERIENTIA | 1991年 / 47卷 / 11-12期

关键词：

ENZYMES; PEPTIDE SYNTHESIS; ENZYME MODIFICATION;

D O I：

10.1007/BF01918376

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This review article describes new enzymatic methods developed for the efficient and irreversible synthesis of peptides based on native and modified proteases, and for the synthesis of polypeptides containing D- and/or unnatural amino acids. Potential opportunities for future developments in the field based on new enzymes, tailor-made catalytic antibodies, and on the technique of in vitro mutagenesis are also described.

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收藏

页码：1123 / 1129

页数：7

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