POTENTIAL ANTI-CANCER AGENTS .14. ISOLATION OF SPRUCEANOL AND MONTANIN FROM CUNURIA-SPRUCEANA (EUPHORBIACEAE)

被引：38

作者：

GUNASEKERA, SP

CORDELL, GA

FARNSWORTH, NR

机构：

[1] Department of Pharmacognosy and Pharmacology, College of Pharmacy, University of Illinois at the Medical Center, Illinois, Chicago

来源：

JOURNAL OF NATURAL PRODUCTS | 1979年 / 42卷 / 06期

关键词：

D O I：

10.1021/np50006a012

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Montanin (1) and spruceanol (2), two quite different diterpenes, were found to be responsible for the cytotoxic and antitumor activity of the root and root bark of Cunuria spruceana (Euphorbiaceae). The structure of spruceanol (2) was deduced from spectral interpretation and chemical correlation with 12-methoxycleistanth-8, 11, 13-trien-3-one (4). © 1979, American Chemical Society. All rights reserved.

引用

页码：658 / 662

页数：5

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