DECREASED GRAY-MATTER IN NORMAL AGING - AN INVIVO MAGNETIC-RESONANCE STUDY

被引：70

作者：

LIM, KO ^{[1
]}

ZIPURSKY, RB ^{[1
]}

WATTS, MC ^{[1
]}

PFEFFERBAUM, A ^{[1
]}

机构：

[1] STANFORD UNIV,MED CTR,SCH MED,DEPT PSYCHIAT & BEHAV SCI,PHYSIOL & STRUCT BRAIN IMAGING LAB,STANFORD,CA 94305

来源：

JOURNALS OF GERONTOLOGY | 1992年 / 47卷 / 01期

关键词：

D O I：

10.1093/geronj/47.1.B26

中图分类号：

R4 [临床医学]; R592 [老年病学];

学科分类号：

1002 ; 100203 ; 100602 ;

摘要：

Using in vivo magnetic resonance (MR) images, the percentages of gray matter, white matter, and cerebrospinal fluid (CSF) in the brains of 8 young and 6 elderly normal male community volunteers were quantified. Compared with the young men, the elderly men had a significantly lower percentage of gray matter (p < .01) and higher percentage of CSF (p < .01). The percentage of white matter was not significantly different between the two groups. This finding suggests that the age-related decrease in brain tissue is chiefly due to loss of gray matter.

引用

页码：B26 / B30

页数：5

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