STUDIES ON THE METABOLITES PRODUCED BY FACULTATIVE METHANOL OXIDIZING BACTERIA .2. FORMATION OF COENZYME Q11 BY PSEUDOMONAS-M16, A MUTANT

Pseudomonas M16 is the mutant derived from a facultative methylotroph, Pseudomonas N842, which is the potent producer of coenzyme Q10 (CoQ10). This mutant with elevated productivity of CoQ10 was observed to accumulate the significant amount of another CoQ homolog, which could not be detected in the parent strain. This CoQ homolog was extracted from the intact cells of the mutant and purified to crystalline state. The chemical properties and the results of UV, NMR and mass spectrometries revealed that this CoQ homolog was CoQ11.