DNA POLYMERASE-EPSILON - IN SEARCH OF A FUNCTION

被引：41

作者：

HUBSCHER, U

THOMMES, P

机构：

[1] Department of Pharmacology and Biochemistry, University of Zürich-Irchel, CH-8057 Zürich

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1992年 / 17卷 / 02期

关键词：

D O I：

10.1016/0968-0004(92)90499-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The current model of eukaryotic DNA replication involves the two DNA polymerases δ and α as the leading and lagging strand enzymes, respectively. A DNA polymerase first discovered in yeast has now been found in all eukaryotic cells and is termed DNA polymerase ε. In yeast, the gene for DNA polymerase ε has recently been found to be essential for viability, raising new questions about its functions. © 1992.

引用

页码：55 / 58

页数：4

共 43 条

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