ANTIHERPETIC IN-VITRO ACTIVITY OF GAMOCHAETA-SIMPLICICAULIS EXTRACT

被引：8

作者：

CAVALLARO, L

GARCIA, G

BROUSSALIS, A

FERRARO, X

MARTINO, V

COUSSIO, J

DETORRES, R

CAMPOS, R

机构：

[1] UNIV BUENOS AIRES, FAC FARM & BIOQUIM, CATEDRA VIROL, RA-1113 BUENOS AIRES, DF, ARGENTINA

[2] UNIV BUENOS AIRES, FAC FARM & BIOQUIM, CATEDRA MICROBIOL, RA-1113 BUENOS AIRES, DF, ARGENTINA

[3] UNIV BUENOS AIRES, FAC FARM & BIOQUIM, CATEDRA FARMACOGNOSIA, RA-1113 BUENOS AIRES, DF, ARGENTINA

来源：

PHYTOTHERAPY RESEARCH | 1995年 / 9卷 / 03期

关键词：

ANTIVIRAL ACTIVITY; AQUEOUS EXTRACTS; GAMOCHAETA SIMPLICICAULIS; VIRAL ADSORPTION; ANTIHERPETIC ACTIVITY;

D O I：

10.1002/ptr.2650090304

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Aqueous extracts of Gamochaeta simplicicaulis present true antiviral activity in vitro against different members of the herpesvirus family (herpes simplex virus types 1 and 2, human cytomegalovirus, bovine herpes virus and lower activity with pseudorabies virus). The extract had no activity against some RNA (naked and enveloped) viruses and adenoviruses. The extract was not virucidal but its antiviral index (An was high enough to justify further analysis. Different experimental approaches indicate that an early step of viral replication, at least the adsorption period, was involved in the antiviral activity.

引用

页码：176 / 179

页数：4

共 19 条

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