COMPARISON OF CEFPODOXIME PROXETIL WITH CEFACLOR IN THE TREATMENT OF SINUSITIS

被引：24

作者：

GEHANNO, P

DEPONDT, J

BARRY, B

SIMONET, M

DEWEVER, H

机构：

[1] HOP NECKER ENFANTS MALAD,F-75730 PARIS 15,FRANCE

[2] HOP UNIV ST PIERRE,B-1000 BRUSSELS,BELGIUM

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1990年 / 26卷

关键词：

D O I：

10.1093/jac/26.suppl_E.87

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The efficacy and tolerance of cefpodoxime proxetil were compared with those of cefaclor in a multicentre, international, prospective, double-blind, placebocontrolled study in adult outpatients suffering from acute sinusitis. At the end of treatment, cefpodoxime proxetil was more effective than cefaclor, producing complete clinical cure in 84% of cases (102/122) vs 68% of cases (77/114) in the cefaclor group (P = 0.01). The overall clinical efficacy (cure + improvement) was similar in the two groups with 95% (116/122) satisfactory responses in the cefpodoxime proxetil group and 93% (106/114) in the cefaclor group. Bacteriological response was similar with 95% eradication in the cefpodoxime proxetil group (55/58) vs 91% with cefaclor (63/69). © 1990 The British Society for Antimicrobial Chemotherapy.

引用

页码：87 / 91

页数：5

共 11 条

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