ACTIVATION OF RYANODINE RECEPTORS BY FLASH-PHOTOLYSIS OF CAGED CA2+

被引：28

作者：

LAMB, GD

STEPHENSON, DG

机构：

[1] School of Zoology, La Trobe University, Bundoora

[2] Melbourne, Victoria

来源：

BIOPHYSICAL JOURNAL | 1995年 / 68卷 / 03期

关键词：

D O I：

10.1016/S0006-3495(95)80270-5

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Flash photolysis of DM-nitrophen generates an extremely large [Ca2+] transient (''Ca2+ spike'') at the start of each Ca2+ ''step.'' The Ca2+ spike greatly increases the speed of activation of the ryanodine receptor channel (''supercharging'') and could be responsible for apparent channel adaptation.

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收藏

页码：946 / 948

页数：3

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