A CONCISE SYNTHESIS OF (+)-MUSCARINE

被引：40

作者：

CHAN, TH

LI, CJ

机构：

[1] Department of Chemistry, McGill University, Montreal

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1992年 / 70卷 / 11期

关键词：

D O I：

10.1139/v92-346

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(+)-Muscarine was synthesized from S-(-)-ethyl lactate in five steps with the application of a zinc-mediated allylation reaction in aqueous media. Reversal of chelation-control stereoselectivity was observed in the allylations of chiral alpha-alkoxy aldehydes in aqueous media.

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页码：2726 / 2729

页数：4

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