外阴上皮内瘤样病变

被引:4
作者
黄勤 [1 ]
王景美 [1 ]
胡娅莉 [2 ]
机构
[1] 南京大学医学院附属鼓楼医院病理科
[2] 不详
关键词
外阴上皮内瘤样病变; 人乳头状瘤病毒; 鳞状细胞癌;
D O I
暂无
中图分类号
R737.35 [外阴部肿瘤];
学科分类号
摘要
外阴上皮内瘤样病变(VIN)是用来描述外阴皮肤鳞状上皮异常增生的一组癌前病变。近年来,其发病率快速上升。基于有无人乳头状瘤病毒(HPV)感染,VIN可分为HPV阳性及阴性两类。前者通常发病年龄较轻,31%40%可能进展为浸润性癌;后者常与硬化性苔藓相关,发生于老年患者,约60%可能进展为浸润性癌。VIN根据形态学特征及病变深度,可分为Ⅰ级、Ⅱ级和Ⅲ级。VIN可自行消退,但也可能进展为浸润性癌。激素治疗可阻止其恶性转化,但不能达到治愈,外科手术切除是浸润性癌的主要治疗手段。
引用
收藏
页码:199 / 202
页数:4
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