腰椎间盘退变的MR定量分析:MRS和T1ρ成像技术附视频

被引：8

作者：

李永 ^{[1
]}

陈雪贞 ^{[2
]}

蔡兆熙 ^{[1
]}

潘园园 ^{[1
]}

张帆 ^{[1
]}

陈建宇 ^{[1
]}

机构：

[1] 中山大学孙逸仙纪念医院放射科

[2] 中山大学孙逸仙纪念医院儿科

来源：

中国医学影像技术 | 2018年 / S1期

基金：

广东省科技计划;

关键词：

椎间盘退变; 磁共振波谱学; 磁共振成像;

D O I：

暂无

中图分类号：

R681.5 [脊柱及背疾病]; R445.2 [核磁共振成像];

学科分类号：

100220 [骨科学]; 100231 [临床病理学];

摘要：

目的探讨MRS和T1ρ成像技术定量评估腰椎间盘的退变程度的应用价值。方法收集腰痛患者64例,按年龄分为<30岁组(10例)、30～39岁组(12例)、40～49岁组(11例)、50～59岁组(15例)、>59岁组(16例)。对每例患者选取2个腰椎间盘进行MRS扫描,获得髓核氮-乙酰氨基峰下面积(N-acetyl)、水峰下面积(Water),及N-acetyl/Water值;并行T1ρ成像,分别测量髓核及纤维环T1ρ值。比较不同Pfirrmann分级及年龄组间MRS及T1ρ定量分析结果的差异,并分析Pfirrmann分级和年龄与T1ρ和MRS定量分析结果的相关性。结果 64例患者共128个椎间盘中,PfirrmannⅡ级61个,Ⅲ级40个,Ⅳ级23个,Ⅴ级4个。不同Pfirrmann分级椎间盘间及不同年龄组间,髓核T1ρ、N-acetyl、Water及N-acetyl/Water值差异均有统计学意义(P均<0.01),纤维环T1ρ值差异无统计学意义(P>0.05)。N-acetyl、Nacetyl/Water、髓核T1ρ值,随Pfirrmann分级增加、患者年龄增大,均呈下降趋势。结论 MRS和T1ρ成像技术均可用于腰椎间盘退变的定量评估,且与Pfirrmann分级具有良好的相关性。

引用

页码：45 / 48

页数：4

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