白癜风免疫发病机制研究进展

被引：21

作者：

杨珂 ^{[1
]}

张学军 ^{[2
]}

机构：

[1] 安徽医科大学第一附属医院皮肤科

[2] 安徽医科大学

来源：

中国麻风皮肤病杂志 | 2012年 / 28卷 / 03期

关键词：

白癜风; 发病机制; 免疫; 自身免疫性疾病;

D O I：

暂无

中图分类号：

R758.41 [];

学科分类号：

摘要：

白癜风是一种以局部表皮黑素细胞减少,形成白斑为特征的后天性色素减退性皮肤病。其发病机制现尚未阐明,遗传及免疫因素在发病中起重要作用。目前支持白癜风是自身免疫性疾病的证据:发现了与免疫功能或自身免疫性疾病密切相关的易感基因和候选基因,如SLEV1、AIS1、HLA等基因;体液免疫和细胞免疫机制均参与了白癜风发病;白癜风患者常合并其他自身免疫性疾病;临床上使用免疫调节疗法治疗白癜风取得了较好的疗效。

引用

页码：188 / 191

页数：4

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