黄芪治疗糖尿病肾病的研究进展

被引：61

作者：

陈腾 ^{[1
,2
]}

简桂花 ^{[2
]}

汪年松 ^{[2
]}

机构：

[1] 上海中医药大学研究生院

[2] 上海市第六人民医院肾脏内科

来源：

中国中西医结合肾病杂志 | 2017年 / 18卷 / 05期

关键词：

D O I：

暂无

中图分类号：

R277.5 [中医泌尿学];

学科分类号：

100221 [泌尿外科学];

摘要：

<正>糖尿病肾病(diabetic nephropathy,DN)是糖尿病(diabetes mellitus,DM)最典型的微血管并发症之一,也是导致糖尿病患者死亡的常见原因。据2015年统计,将近40%的美国DM患者合并DN,DN是导致终末期肾病(end stage renal disease,ESRD)的主要病因。现在临床上对DN的防治主要包括以下方面:调整生活方式和饮食,控制血糖、血压,纠正血脂紊乱,调控蛋白尿等;对于肾衰竭的患者是以透析或肾移植为主要治疗

引用

页码：462 / 464

页数：3

共 22 条

[1]

Modulatory Effects of Astragalus Polysaccharides on T-Cell Polarization in Mice with Polymicrobial Sepsis.[J].Yu-Chen Hou;Jin-Ming Wu;Ming-Yang Wang;Ming-Hsun Wu;Kuen-Yuan Chen;Sung-Ling Yeh;Ming-Tsan Lin;Simi Ali.Mediators of Inflammation.2015,

[2]

Astragalus polysaccharides affect insulin resistance by regulating the hepatic SIRT1-PGC-1α/PPARα-FGF21 signaling pathway in male Sprague Dawley rats undergoing catch-up growth [J].

Gu, Chengying ;

Zeng, Yipeng ;

Tang, Zhaosheng ;

Wang, Chaoxun ;

He, Yanju ;

Feng, Xinge ;

Zhou, Ligang .

MOLECULAR MEDICINE REPORTS, 2015, 12 (05) :6451-6460

[3]

Astragaloside IV prevents damage to human mesangial cells through the inhibition of the NADPH oxidase/ROS/Akt/NF-κB pathway under high glucose conditions [J].

Sun, Li ;

Li, Weiping ;

Li, Weizu ;

Xiong, Li ;

Li, Guiping ;

Ma, Rong .

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2014, 34 (01) :167-176

[4]

Astragaloside IV ameliorates diabetic nephropathy involving protection of podocytes in streptozotocin induced diabetic rats.[J].Jianguo Chen;Yifang Chen;Yunling Luo;Dingkun Gui;Jianhua Huang;Dongyuan He.European Journal of Pharmacology.2014,

[5]

Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression [J].

Gui, Dingkun ;

Huang, Jianhua ;

Guo, Yongping ;

Chen, Jianguo ;

Chen, Yifang ;

Xiao, Wenzhen ;

Liu, Xusheng ;

Wang, Niansong .

CYTOKINE, 2013, 61 (03) :970-977

[6]

Meta-analysis of the clinical value of Astragalus membranaceus in diabetic nephropathy.[J].Mingxin Li;Weixin Wang;Jun Xue;Yong Gu;Shanyan Lin.Journal of Ethnopharmacology.2010, 2

[7]

Merit of Astragalus polysaccharide in the improvement of early diabetic nephropathy with an effect on mRNA expressions of NF-κB and IκB in renal cortex of streptozotoxin-induced diabetic rats [J].