超脉冲点阵CO2激光联合外涂硅凝胶治疗面颈部深Ⅱ度烧伤后增生性瘢痕

被引:9
作者
田小瑞 [1 ]
王建明 [1 ]
郭万里 [2 ]
马冰 [1 ]
张书欣 [1 ]
刘鼎 [1 ]
机构
[1] 太原钢铁(集团)有限公司总医院创面修复外科
[2] 太原钢铁(集团)有限公司总医院烧伤一科
关键词
面颈部; 深Ⅱ度烧伤; 增生性瘢痕; 超脉冲点阵CO2激光; 硅凝胶; 临床疗效;
D O I
暂无
中图分类号
R644 [烧伤及烫伤(灼伤)];
学科分类号
100227 [皮肤病学];
摘要
目的:观察超脉冲点阵CO2激光联合硅凝胶对面颈部深Ⅱ度烧伤后增生性瘢痕(Hypertrophic scar,HS)的临床效果。方法:选择2020年5月-2023年2月笔者医院收治的118例面颈部深Ⅱ度烧伤后HS患者,采用随机数字表法分为对照组(给予硅凝胶治疗,59例)和联合组(给予超脉冲点阵CO2激光联合硅凝胶治疗,59例)。对比两组患者临床疗效、视觉模拟疼痛量表(Visual analogue scale,VAS)评分、温哥华瘢痕量表(Vancouver scar scale,VSS)评分、瘢痕厚度、瘢痕回声密度、生长因子指标[转化生长因子-β1(Transforming growth factor-β1,TGF-β1)、表皮生长因子(Epidermal growth factor,EGF)]及不良反应发生情况。结果:治疗3个月后,联合组总有效率为98.31%,高于对照组的84.75%(P<0.05);联合组VAS、VSS评分均低于对照组(P<0.05);联合组瘢痕厚度低于对照组(P<0.05),瘢痕回声密度则高于对照组(P<0.05);联合组TGF-β1、EGF水平均低于对照组(P<0.05)。治疗期间,联合组和对照组不良反应发生率分别为11.86%和8.47%,但差异无统计学意义(P>0.05)。结论:超脉冲点阵CO2激光联合硅凝胶治疗面颈部深Ⅱ度烧伤后HS患者可提高临床疗效,缓解疼痛症状,改善瘢痕情况,促进瘢痕消退,调节生长因子水平,且安全可靠。
引用
收藏
页码:14 / 18
页数:5
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